Skin & renewal
This page provides detailed, clear information about Polynucleotides (PN). Before a plan is agreed, your needs, medical history and suitability are assessed individually. Polynucleotide applications refer to products administered intradermally for selected skin quality expectations. Product content, source material, license status and proposed area of use should be clearly stated in the consultation.
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01 / About this procedure
This page provides detailed, clear information about Polynucleotides (PN). Before a plan is agreed, your needs, medical history and suitability are assessed individually.
Polynucleotide applications refer to products administered intradermally for selected skin quality expectations. Product content, source material, license status and proposed area of use should be clearly stated in the consultation.
Scientific evidence varies by product, region and target. Therefore, PN should not be presented as a single standard protocol or guaranteed method of renewal.
During the consultation, your intended change, daily schedule and priorities are considered together, so possible benefits, timing and aftercare needs form a plan you can understand.
The expected change is usually a modest improvement in skin appearance and quality rather than volume creation. The first injection swellings are not the result and recommending several sessions does not mean a definitive answer.
Since the level of evidence varies depending on the product and area of use, a certain renewal percentage, permanence or the same result cannot be promised for everyone. A planned evaluation should be made with photographs and skin findings.
In the evaluation, the type of skin problem, target area, allergy history, and the full trade name and source of the product are considered together. There may be products under the name PN with different content, density and usage instructions.
In particular, fish-derived ingredient sensitivity, autoimmune disease, active infection, pregnancy or breast-feeding, and previous injection reactions should be questioned. Proof of the product for the target area should also be described.
PN does not correct significant volume loss like a filler and does not replace surgical procedures.
Even if the marketing names are the same, the density, source and usage instructions of the products may be different.
History of allergy, active infection, pregnancy or breastfeeding, immune problems, and medications used should be considered in the suitability assessment.
Depending on the target, medical skin care, skin booster, PRP, microneedling, peeling or energy-based procedures can be evaluated. Filler in case of volume loss; For significant laxity, surgery or device options may be more relevant.
Sessions recommended in packages must be justified by product instructions, target and skin response. It should not be repeated automatically without re-evaluating the benefits, side effects and desire to continue at each check-up.
The registration status of the product in the country and its proposed use should be verified through the official product information rather than the marketing name.
02 / Your procedure pathway
YOUR ISTANBUL VISIT
How and where your appointment takes place is confirmed individually with the partner clinic before booking.
03 / Recovery & aftercare
Swelling, redness, tenderness, or bruising may occur at the injection points; Do not squeeze the area and do not apply unplanned products.
Follow the clinic's schedule for intense heat, exercise, pool and other skin procedures.
Seek medical evaluation for increasing swelling, widespread rash, shortness of breath, severe pain, discharge, or persistent nodule.
This content is provided for general information. It does not constitute a diagnosis, personalised medical advice or a guarantee of procedure results. Suitability, method, risks and the follow-up plan are determined through a face-to-face assessment by the relevant healthcare professional.
Redness, swelling, bruising, tenderness, infection, nodules and allergic reactions may occur. Differences in the evidence and between products must be explained clearly.
Product selection and injection must be undertaken by a physician familiar with the ingredients and instructions for use, and competent in skin injections and complication management.
04 / Procedure questions
What is the exact name, source and intended use of the product?
What scientific evidence is based on this region?
By what criteria was the recommended number of sessions determined?
What is the follow-up plan if an adverse reaction occurs?
No. Evidence and response vary by product, use, and individual characteristics; Definitive results should not be promised.
No. The intended use and texture effect are different from filler products; Significant contour volume should not be expected.
Instead of a fixed number, product instructions, target and skin response should be evaluated.
Full product information regarding ingredients, allergies and suitability is required.
YOUR BOOKING JOURNEY
A coordinator helps turn your goals and travel plans into clear next steps with a partner clinic.
Tell us what you are considering, your questions and preferred travel dates.
A coordinator replies in your language, reviews practical needs and explains the available next step.
A partner clinic and qualified clinician review your information, then discuss suitability, options, risks and expected recovery.
The clinic, clinician, date, scope and practical details are confirmed with you before anything is booked.
If you choose, we help coordinate arrival, clinic timing and practical follow-up around your Istanbul visit.
This page provides detailed, clear information about PRP. Before a plan is agreed, your needs, medical history and suitability are assessed individually. PRP involves processing the blood taken from the person to obtain a platelet-rich preparation and applying it to the selected area. The preparation system and protocol may affect the outcome.
This page provides detailed, clear information about Mesotherapy. Before a plan is agreed, your needs, medical history and suitability are assessed individually. Mesotherapy describes small injections into the skin or scalp; It is not a single standard medicine or mixture. Content and purpose may vary in each protocol.
This page provides detailed, clear information about Skin Boosters. Before a plan is agreed, your needs, medical history and suitability are assessed individually. Skin booster is a broad expression used for different injection products aimed at skin moisture and quality expectations. Content, intensity and procedure protocol vary depending on the product.
The first question in the polynucleotide consultation is which product is recommended for which skin target. Disclosure of ingredient source information and site-specific evidence provides more concrete information than making decisions based on a popular app name alone. This guide addresses questions that may be asked during the examination and the limits of expectation of PN.
PN preparation does not only consist of determining the appointment time. Allergy history, product registration, injection site, and social calendar should be considered together. Gathering accurate information before the procedure helps you understand the purpose of the session and know what findings to follow afterward. Create your personal plan with your physician.
In post-PN care, it is important to distinguish between early injection wheals and late reactions. The trip and social program should also take into account control access. This guide covers returning to daily routine, keeping the product record, and accessing health support in case of unexpected symptoms in terms of post-procedure follow-up.
Share your goals and travel dates. We coordinate the practical next step with a partner clinic; a qualified clinician decides what is suitable for you.
